At FAVON, Process R&D is a dedicated service focused on transforming promising synthetic concepts into robust, scalable, and manufacturing-ready chemical processes.
Our role is to remove technical, safety, and regulatory uncertainty before significant investment into kilo-scale or production manufacturing.

All Process R&D activities are executed under our proprietary FoQuS™ – FAVON Quality System, ensuring disciplined decision-making, full traceability, and alignment with expectations for pharmaceutical intermediates.

Process R&D at FAVON is where processes are defined, locked, and made transferable.

 

What We Do in Process R&D

Process R&D at FAVON integrates route design, optimization, safety, impurity control, and analytics into a single, governed development phase.

Core Scope

Route Design and Evaluation

We assess and compare alternative synthetic routes based on scalability, operational safety, cost drivers, and impurity risk. Only routes that demonstrate clear suitability for scale-up and reliable transfer are selected for further development.

Process Optimization and Robustness

We build process understanding through reaction and kinetic analysis, followed by targeted optimization to improve yield and selectivity. Solvents, reagents, and catalysts are systematically optimized, operating windows and critical process parameters are defined, and reproducibility is validated through repeated experimental runs.

Impurity and Control Strategy

Process-related impurities are identified and tracked throughout development. We perform root-cause analysis to understand impurity formation and implement effective reduction and control strategies, including impurity reference synthesis where required.

Safety and Risk Assessment

Each process is evaluated for reaction hazards, thermal risks, gas evolution, and pressure-related challenges. Mitigation measures are defined, tested, and documented to ensure safe and controlled operation under scale-relevant conditions.

Analytical Integration

Process R&D is supported by integrated analytical control using NMR, LC, GC, LC-MS, GC-MS, IR, DSC etc. Stability and stress testing are performed where appropriate, with all analytical data managed under FoQuS™ documentation control.

FoQuS™ Governance and Deliverables

Process R&D at FAVON is executed under formal FoQuS™ governance, ensuring development is driven by controlled decision-making rather than ad-hoc experimentation. All activities follow defined documentation standards, structured change control, and clearly established development milestones. This framework provides full traceability of materials, data, and process parameters, creating a robust and auditable foundation ready for scale-up or technology transfer.

At the conclusion of Process R&D, clients receive a defined and reproducible chemical process supported by a documented impurity and control strategy and a safety-reviewed operating framework. The outcome is a complete, manufacturing-ready process package that can be transferred seamlessly to kilo-scale operations, industrial manufacturing, or external partners under controlled conditions.

Transition to Scale – output of Process R&D can be seamlessly:

Empowering Chemistry means delivering processes that are controlled, scalable, and ready for real manufacturing environments.